스킵 네비게이션


Retinol and Derivative

Development of Retinol and Derivative

 

Retinol

After being consumed, Retinol as pure vitamin A, is broken down into Retinoic Acid. Retinol has attracted considerable attention lately as new functional material that plays an important role in epidermal cells to maintain their original capacity. Retinol promotes cell specialization, activating DNA in the skin cells to express RNA and accelerates the biosynthesis of collagen, elastin and so on. Having this ability, Retinol decreases wrinkles and enhances skin resilience. Also, Retinol controls cell multiplication, prevents the growth of cancer cells if ingested in thel body. Furthermore it maintains an important role in providing immunity from disease, for example leukaemia, as well as possesing anti-inflammatory agents.

Market Situation

Considering Retinols ability, it has a powerful effect within cosmetics and pharmaceutical companies at present.
Retinol's market is quickly expanding to become a huge market. Last year (2000) total sales in Korea was approximately \60 billion in Korea and approximately \ 1,500 billion worldwide.
The active ingredient retinol is extremly sensitive to O2, heat and sunlight. Therefore, great care is required in storage, transportation and processing. Due to this reality, production has its challenges. We have succeeded in stabilizing Retinol, our team of scientists are very proud of this accomplishment.
The domestic demand for Retinol is constant increasing and forecasted to continue, however, Retinol is still heavily imported from foreign companies. Additionally, existing Retinol takes too long to produce and it is very costly because of using a total synthesis method.

Business Direction

Chebigen is conducting research with the aim of developing new retinol derivatives that have retinol and retinol effects that improve the functionality and stability of existing products by utilizing our biotechnology and organic synthesis technology.
In addition, we are developing the technology to produce high value-added retinol from low-cost raw materials, and we are devoting our utmost efforts to derive the maximum added value by reducing the production cost to a considerable level compared to the conventional synthetic method.Currently, we are conducting experiments on production conditions and enzymatic biosynthesis studies by securing genes for the development of new methods for the mass production of retinol, and have already completed derivatives with improved stability.
We are continuing our research on new derivatives that are more effective / toxic than the currently derived derivatives, with the goal of establishing specialization and sequencing of the retinol field by using the total R & D strategy in the field of retinol.